Alzheimer's disease and role of choroidal epithelial cells - an in-vitro study
Téma již má řešitele.- Řešitel
- Eliška Drdová - Klvaňovo Gymnázium a střední Zdravotnická škola Kyjov
- Instituce
- Masarykova univerzita
- Fakulta/ústav
- Fakulta lékařská
- Další údaje o pracovišti
- Anatomy
- Lektoři
- Alemeh Zamani
- Podpora
- JCMM podpořila toto SOČ téma částkou 20 000 Kč na materiál a částkou 10 000 Kč na honorář školitele.
Our laboratory has developed an in vitro model of Alzheimer's disease through the hard work of our SOČ students. Using this model, we have investigated how the aggregation of amyloid-β (Aβ), a hallmark of Alzheimer’s disease, affects choroidal epithelial cells. These cells are essential for brain function, as they play a critical role in clearing Aβ from the brain and can prevent Aβ aggregation and toxicity.
Expanding upon the findings of our previous SOČ students, we are offering an internship opportunity to study the molecular changes in choroidal epithelial cells (Z310 cells) associated with Alzheimer’s disease. During the internship, you will receive training in a variety of research techniques, including cell culture and microscopy.